MIR9-1HG

Across TCGA patient cohorts, MIR9-1HG mutation is significantly associated with the RNA expression of many other genes, with 1,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR9-1HG-associated genes across cancer lineages are NGRN, TSSC4, and UBE2L3. Each is linked with MIR9-1HG in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR9-1HG-to-partner and partner-to-MIR9-1HG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NGRN grouped by MIR9-1HG-low versus MIR9-1HG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR9-1HG→partner) and Y-score (partner→MIR9-1HG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NGRN →	+0.676	+2.711	<.001	.003	3	2
UCEC	TSSC4 →	+0.480	+3.475	.004	.002	3	2
UCEC	UBE2L3 →	+0.395	+3.330	.002	.005	3	2
CESC	KRTAP4-3 →	+0.069	+5.263	<.001	.001	3	2
CESC	MAGEA4-AS1 →	+1.025	+3.709	.004	.006	3	2
LUSC	RNU6-717P →	+0.262	+7.924	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,132 associations by consensus.

NGRN by MIR9-1HG expression — UCEC

Explore this box plot interactively →