MIR9-1HG

Across TCGA pan-cancer cohorts, MIR9-1HG RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MIR9-1HG data layer compared with 5 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MIR9-1HG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR9-1HG expression acts as an unfavorable survival marker, although some lineages such as CESC and LGG show a favorable association.

ACC, CESC, and KIRP are the cancer types where MIR9-1HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.299	0.800	<.001	106	view →
CESC	OS	Median	II,III,IV	0.731	0.330	<.001	66	view →
KIRP	OS	Tertile	All	0.538	0.800	.001	64	view →
ESCA	DFS	Quartile	All	0.373	0.698	<.001	60	view →
KIRC	DFS	Tertile	II,III,IV	0.396	0.637	<.001	47	view →
KICH	OS	Median	III,IV	0.759	1.000	.005	47	view →
THYM	DFS	Median	All	0.820	0.962	.002	42	view →
STAD	DFS	Tertile	II,III,IV	0.487	0.694	.004	39	view →
LGG	OS	Tertile	All	0.928	0.818	<.001	33	view →
MESO	OS	Quartile	All	0.269	0.529	.004	23	view →
SKCM	OS	Tertile	IV	0.599	0.109	.002	23	view →
UCEC	DFS	Quartile	All	0.850	0.932	.006	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MIR9-1HG–ACC (DFS)

Open the ACC breakdown →