MIR9-1HG

Across TCGA patient cohorts, MIR9-1HG mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR9-1HG-associated genes across cancer lineages are Akt_pT308, Tuberin_pT1462, and ASNS. Each is linked with MIR9-1HG in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR9-1HG-to-partner and partner-to-MIR9-1HG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Akt_pT308 grouped by MIR9-1HG-low versus MIR9-1HG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR9-1HG→partner) and Y-score (partner→MIR9-1HG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Akt_pT308 →	+0.735	+2.459	.015	.020	3	2
UCEC	Tuberin_pT1462 →	+0.465	+3.584	<.001	.002	3	2
UCEC	ASNS →	+0.708	+3.321	<.001	.010	3	2
UCEC	ATM →	-0.493	-2.459	.024	.020	3	2
UCEC	Ku80 →	+0.298	+2.472	.009	.011	3	1
UCEC	PRAS40_pT246 →	+0.271	+2.472	.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Akt_pT308 by MIR9-1HG expression — UCEC

Explore this box plot interactively →