MIR8078

Across TCGA patient cohorts, MIR8078 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible MIR8078-associated genes across cancer lineages are RNU6-591P, BSNDP4, and FAM197Y6. Each is linked with MIR8078 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR8078-to-partner and partner-to-MIR8078 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-591P grouped by MIR8078-low versus MIR8078-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR8078→partner) and Y-score (partner→MIR8078) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-591P →	+0.547	+8.066	<.001	.007	3	2
LUSC	BSNDP4 →	+0.291	+5.474	<.001	.005	3	2
LUSC	FAM197Y6 →	+1.111	+5.792	<.001	.003	3	2
LUSC	TPM3P3 →	+0.122	+5.404	<.001	.005	3	2
SKCM	ELOCP14 →	+0.104	+7.816	<.001	.008	3	1
COAD	MTND5P6 →	+0.114	+5.484	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

RNU6-591P by MIR8078 expression — UCEC

Explore this box plot interactively →