MIR8074

Across TCGA patient cohorts, MIR8074 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,372 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR8074-associated GO terms across cancer lineages are Negative regulation of centrosome duplication, Positive regulation of double-strand break repair via nonhomologous end joining, and Positive regulation of insulin secretion. Each is linked with MIR8074 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR8074-to-partner and partner-to-MIR8074 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of centrosome duplication grouped by MIR8074-low versus MIR8074-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR8074→partner) and Y-score (partner→MIR8074) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of centrosome duplication →	+0.135	+0.153	<.001	<.001	3	3
STAD	Positive regulation of double-strand break repair via nonhomologous end joining →	+0.133	+0.151	<.001	<.001	3	3
STAD	Positive regulation of insulin secretion →	+0.086	+0.120	<.001	<.001	3	3
STAD	Insulin secretion involved in cellular response to glucose stimulus →	+0.094	+0.124	<.001	<.001	3	3
STAD	Cellular lipid catabolic process →	+0.109	+0.147	<.001	<.001	3	3
STAD	Regulation of endosome size →	+0.125	+0.147	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,372 associations by consensus.

Negative regulation of centrosome duplication by MIR8074 expression — STAD

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