MIR8066

Across TCGA patient cohorts, MIR8066 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,502 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR8066-associated GO terms across cancer lineages are Telomerase holoenzyme complex assembly, Negative regulation of mRNA processing, and rRNA base methylation. Each is linked with MIR8066 in more than 5 cancer types. Because this analysis shows association rather than direction, both MIR8066-to-partner and partner-to-MIR8066 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomerase holoenzyme complex assembly grouped by MIR8066-low versus MIR8066-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR8066→partner) and Y-score (partner→MIR8066) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Telomerase holoenzyme complex assembly →	+0.054	+0.150	<.001	<.001	3	6
ESCA	Negative regulation of mRNA processing →	+0.061	+0.541	<.001	<.001	3	6
STAD	rRNA base methylation →	+0.033	+0.504	<.001	<.001	3	6
ESCA	Alternative mRNA splicing, via spliceosome →	+0.070	+0.428	<.001	.004	2	6
ESCA	Protection from natural killer cell mediated cytotoxicity →	+0.058	+0.452	<.001	.001	2	6
ESCA	Regulation of mRNA splicing, via spliceosome →	+0.071	+0.452	<.001	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,502 associations by consensus.

Telomerase holoenzyme complex assembly by MIR8066 expression — UCEC

Explore this box plot interactively →