MIR8053

Across TCGA patient cohorts, MIR8053 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,299 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR8053-associated GO terms across cancer lineages are Negative regulation of Wnt signaling pathway, Negative regulation of protein localization, and Osteoblast differentiation. Each is linked with MIR8053 in more than 7 cancer types. Because this analysis shows association rather than direction, both MIR8053-to-partner and partner-to-MIR8053 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of Wnt signaling pathway grouped by MIR8053-low versus MIR8053-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR8053→partner) and Y-score (partner→MIR8053) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of Wnt signaling pathway →	+0.079	+0.095	<.001	<.001	3	7
ESCA	Negative regulation of protein localization →	+0.125	+0.205	<.001	.006	2	7
STAD	Osteoblast differentiation →	+0.087	+0.099	<.001	<.001	3	6
STAD	Glycerophospholipid biosynthetic process →	+0.114	+0.107	<.001	<.001	3	6
ESCA	Nucleobase-containing compound transport →	+0.143	+0.121	<.001	.002	3	6
ESCA	Cytosolic transport →	+0.131	+0.115	<.001	.003	1	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,299 associations by consensus.

Negative regulation of Wnt signaling pathway by MIR8053 expression — STAD

Explore this box plot interactively →