MIR8053

Across TCGA pan-cancer cohorts, MIR8053 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR8053’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR8053 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR8053 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

BRCA and KIRC are the cancer types where MIR8053 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR8053 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.094	.048	2	view →
KIRC	Male	All	−0.047	.045	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MIR8053–BRCA

Open the BRCA breakdown →