MIR7849

Across TCGA pan-cancer cohorts, MIR7849 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MIR7849 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR7849 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR7849 expression acts as an unfavorable survival marker, although some lineages such as OV and KIRC show a favorable association.

UVM, COAD, and THCA are the cancer types where MIR7849 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	III,IV	0.203	0.729	<.001	54	view →
COAD	OS	Tertile	II,III,IV	0.623	0.865	.003	42	view →
THCA	OS	Tertile	IV	0.719	0.972	<.001	36	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	27	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →
OV	DFS	Tertile	III,IV	0.675	0.518	.023	12	view →
SKCM	OS	Tertile	III,IV	0.656	0.818	.025	6	view →
KIRC	DFS	Tertile	IV	0.715	0.233	.031	6	view →
LUSC	DFS	Tertile	All	0.282	0.414	.018	6	view →
STAD	DFS	Quartile	IV	0.097	0.416	.014	3	view →
LGG	OS	Tertile	All	0.957	0.871	.042	3	view →
LAML	DFS	Tertile	All	0.638	0.413	.041	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MIR7849–UVM (DFS)

Open the UVM breakdown →