MIR6859-4

Across TCGA patient cohorts, MIR6859-4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,509 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MIR6859-4-associated GO terms across cancer lineages are Regulation of Arp2/3 complex-mediated actin nucleation, Regulation of actin nucleation, and Positive regulation of DNA repair. Each is linked with MIR6859-4 in more than 24 cancer types. Because this analysis shows association rather than direction, both MIR6859-4-to-partner and partner-to-MIR6859-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Arp2/3 complex-mediated actin nucleation grouped by MIR6859-4-low versus MIR6859-4-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6859-4→partner) and Y-score (partner→MIR6859-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Regulation of Arp2/3 complex-mediated actin nucleation →	+0.041	+1.066	<.001	<.001	3	25
GBM	Regulation of actin nucleation →	+0.035	+0.854	<.001	<.001	2	25
UVM	Positive regulation of DNA repair →	+0.030	+0.631	<.001	<.001	3	23
DLBC	Epigenetic regulation of gene expression →	+0.053	+1.227	.006	.001	2	23
DLBC	Regulation of RNA splicing →	+0.049	+0.815	.006	.003	3	22
ESCA	Arp2/3 complex-mediated actin nucleation →	+0.035	+1.104	<.001	<.001	2	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,509 associations by consensus.

Regulation of Arp2/3 complex-mediated actin nucleation by MIR6859-4 expression — LAML

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