MIR6859-4

Across TCGA patient cohorts, MIR6859-4 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR6859-4-associated genes across cancer lineages are OR13F1, SMIM11P1, and RNA5SP98. Each is linked with MIR6859-4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR6859-4-to-partner and partner-to-MIR6859-4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13F1 grouped by MIR6859-4-low versus MIR6859-4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6859-4→partner) and Y-score (partner→MIR6859-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR13F1 →	+0.107	+4.038	.005	.004	3	1
UCEC	SMIM11P1 →	+0.481	+5.384	<.001	<.001	3	1
UCEC	RNA5SP98 →	+0.789	+4.352	<.001	.008	3	1
UCEC	RNU4-80P →	+0.645	+5.163	.005	<.001	3	1
UCEC	RNA5SP205 →	+0.569	+4.267	<.001	.009	3	1
UCEC	RNU6-200P →	+0.300	+5.660	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

OR13F1 by MIR6859-4 expression — UCEC

Explore this box plot interactively →