MIR6859-3

Across TCGA patient cohorts, MIR6859-3 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR6859-3-associated genes across cancer lineages are MIR1266, RNU6-380P, and VCY1B. Each is linked with MIR6859-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR6859-3-to-partner and partner-to-MIR6859-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1266 grouped by MIR6859-3-low versus MIR6859-3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6859-3→partner) and Y-score (partner→MIR6859-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR1266 →	+0.399	+4.771	<.001	<.001	3	2
UCEC	RNU6-380P →	+0.350	+5.470	<.001	.001	3	2
BRCA	VCY1B →	+0.073	+7.731	<.001	.009	3	1
BRCA	DEFT1P →	+1.097	+8.055	<.001	.007	3	1
BRCA	RN7SKP33 →	+0.119	+7.731	<.001	.009	3	1
BRCA	RN7SL400P →	+0.514	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

MIR1266 by MIR6859-3 expression — UCEC

Explore this box plot interactively →