MIR6859-3

Across TCGA pan-cancer cohorts, MIR6859-3 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR6859-3 data layer compared with 2 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR6859-3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR6859-3 expression acts as an unfavorable survival marker, although some lineages such as ESCA and SKCM show a favorable association.

KIRC, UVM, and PAAD are the cancer types where MIR6859-3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	II,III,IV	0.217	0.760	.010	66	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	54	view →
PAAD	OS	Tertile	All	0.094	0.640	<.001	36	view →
CESC	OS	Tertile	III,IV	0.068	0.756	<.001	36	view →
LIHC	OS	Tertile	All	0.194	0.691	.009	36	view →
ESCA	DFS	Quartile	II,III,IV	0.661	0.440	.017	21	view →
THYM	DFS	Tertile	II,III,IV	0.145	0.873	<.001	18	view →
BLCA	OS	Tertile	III,IV	0.197	0.684	.013	18	view →
ACC	DFS	Tertile	All	0.078	0.634	.001	18	view →
SKCM	DFS	Tertile	IV	1.000	0.241	.021	12	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR6859-3–KIRC (DFS)

Open the KIRC breakdown →