MIR6859-2

Across TCGA pan-cancer cohorts, MIR6859-2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MIR6859-2 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher MIR6859-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR6859-2 expression acts as an unfavorable survival marker, although some lineages such as PAAD and SARC show a favorable association.

LUSC, TGCT, and MESO are the cancer types where MIR6859-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	II,III,IV	0.449	0.647	.004	34	view →
TGCT	DFS	Quartile	II,III,IV	0.587	1.000	.004	32	view →
MESO	DFS	Quartile	IV	0.079	0.468	<.001	27	view →
COAD	DFS	Tertile	All	0.694	0.802	.013	21	view →
LIHC	DFS	Tertile	All	0.448	0.574	.013	13	view →
PRAD	DFS	Tertile	All	0.833	0.908	.011	12	view →
PAAD	OS	Tertile	All	0.556	0.257	.025	11	view →
SARC	DFS	Quartile	All	0.717	0.417	.002	10	view →
GBM	DFS	Tertile	All	0.148	0.255	.033	9	view →
ACC	OS	Tertile	IV	0.353	0.751	.028	9	view →
BRCA	DFS	Tertile	All	0.927	0.955	.031	6	view →
HNSC	OS	Tertile	All	0.773	0.659	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MIR6859-2–LUSC (DFS)

Open the LUSC breakdown →