MIR6730

Across TCGA pan-cancer cohorts, MIR6730 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR6730 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR6730 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MIR6730 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, ACC, and UVM are the cancer types where MIR6730 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.527	0.282	<.001	81	view →
ACC	OS	Quartile	II,III,IV	0.194	0.787	.003	42	view →
UVM	OS	Tertile	II,III,IV	0.104	0.829	<.001	36	view →
PRAD	DFS	Quartile	All	0.741	0.907	<.001	36	view →
SKCM	OS	Quartile	All	0.860	0.753	.009	19	view →
THYM	OS	Median	II,III,IV	0.884	1.000	.008	17	view →
BRCA	OS	Quartile	All	0.984	0.955	.012	16	view →
LGG	DFS	Quartile	All	0.729	0.876	.001	15	view →
GBM	DFS	Quartile	All	0.198	0.329	.010	12	view →
THCA	OS	Tertile	II,III,IV	1.000	0.326	.004	12	view →
KICH	DFS	Quartile	III,IV	0.180	0.738	.003	10	view →
DLBC	DFS	Tertile	All	0.301	0.799	.030	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR6730–HNSC (OS)

Open the HNSC breakdown →