MIR6730

Across TCGA pan-cancer cohorts, MIR6730 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR6730’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MIR6730 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR6730 is over-expressed in tumor, although a few such as BRCA and READ show the opposite, repressed pattern.

THCA, KIRC, and BRCA are the cancer types where MIR6730 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR6730 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	II,III,IV	+1.938	<.001	9	view →
KIRC	All	All	+0.339	.002	7	view →
BRCA	All	II,III,IV	−0.512	<.001	6	view →
READ	Male	All	−1.376	.023	4	view →
PAAD	All	All	+1.792	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MIR6730–THCA

Open the THCA breakdown →