Across TCGA pan-cancer cohorts, MIR670HG RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MIR670HG’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR670HG RNA is repressed in tumor relative to normal tissue. In most cancer types MIR670HG is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.
KIRC, THCA, and UCEC are the cancer types where MIR670HG tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR670HG RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.