MIR6499

Across TCGA patient cohorts, MIR6499 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,205 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIR6499-associated GO terms across cancer lineages are Regulation of keratinocyte proliferation, Regulation of epidermis development, and Cranial nerve development. Each is linked with MIR6499 in more than 7 cancer types. Because this analysis shows association rather than direction, both MIR6499-to-partner and partner-to-MIR6499 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of keratinocyte proliferation grouped by MIR6499-low versus MIR6499-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6499→partner) and Y-score (partner→MIR6499) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of keratinocyte proliferation →	+0.036	+0.605	.001	<.001	3	8
ESCA	Regulation of epidermis development →	+0.055	+0.915	<.001	<.001	3	8
ESCA	Cranial nerve development →	+0.039	+0.683	<.001	<.001	3	7
UCEC	Molting cycle process →	+0.045	+0.091	<.001	.002	3	7
CESC	Desmosome organization →	+0.071	+0.461	<.001	<.001	3	7
BRCA	Negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation →	+0.046	+0.079	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,205 associations by consensus.

Regulation of keratinocyte proliferation by MIR6499 expression — ESCA

Explore this box plot interactively →