MIR6089

Across TCGA pan-cancer cohorts, MIR6089 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated MIR6089 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher MIR6089 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR6089 expression acts as an unfavorable survival marker, although some lineages such as OV and STAD show a favorable association.

DLBC, BLCA, and HNSC are the cancer types where MIR6089 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	90	view →
BLCA	OS	Tertile	All	0.225	0.697	<.001	63	view →
HNSC	DFS	Tertile	II,III,IV	0.223	0.621	<.001	63	view →
ESCA	OS	Tertile	All	0.207	0.955	<.001	50	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	39	view →
ACC	OS	Tertile	All	0.214	0.820	.006	36	view →
LGG	OS	Tertile	All	0.638	0.821	.001	33	view →
LUSC	OS	Tertile	II,III,IV	0.364	0.636	.022	27	view →
LIHC	OS	Tertile	III,IV	0.094	0.615	<.001	18	view →
OV	OS	Tertile	II,III,IV	0.747	0.672	.045	12	view →
PCPG	DFS	Tertile	All	0.619	0.944	<.001	9	view →
STAD	DFS	Tertile	All	0.717	0.594	.029	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

MIR6089–DLBC (OS)

Open the DLBC breakdown →