Across TCGA pan-cancer cohorts, MIR6089 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR6089’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where MIR6089 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR6089 is over-expressed in tumor.
ESCA and READ are the cancer types where MIR6089 tumor–normal differential expression is most reproducible.