MIR600HG

Across TCGA pan-cancer cohorts, MIR600HG RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of MIR600HG’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where MIR600HG RNA is repressed in tumor relative to normal tissue. In most cancer types MIR600HG is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and THCA are the cancer types where MIR600HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR600HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	−0.957	<.001	11	view →
KIRC	Male	II,III,IV	−0.915	<.001	11	view →
THCA	Female	II,III,IV	−0.747	<.001	9	view →
LIHC	Female	II,III,IV	+0.797	<.001	7	view →
LUAD	All	II,III,IV	−0.751	<.001	7	view →
COAD	All	II,III,IV	−0.463	<.001	7	view →
BRCA	Female	All	−0.416	<.001	6	view →
CHOL	All	All	+1.748	<.001	5	view →
KICH	Female	II,III,IV	+1.078	.012	4	view →
HNSC	Female	IV	−0.835	.006	4	view →
ESCA	Female	All	−0.813	.005	2	view →
BLCA	Male	IV	−0.772	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

MIR600HG–KIRP

Open the KIRP breakdown →