Q-omics provides the consensus-scored MIR589 profile across patient tissues and cancer cell-line models. MIR589 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, MIR589 is differentially expressed in 9, with the highest sampling consensus in HNSC. Additionally, MIR589 RNA expression shows 14,948 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, HNSC, and TGCT as cancer lineages where MIR589 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR589 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR589 survival associations across molecular data types. MIR589 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR589 RNA expression–survival associations across cancer types. High MIR589 expression shows unfavorable associations in KIRC, KICH, COAD, CESC, LIHC and ACC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for MIR589 RNA expression.
This table summarizes MIR589 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR589. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR589 shows higher tumor expression in HNSC, COAD, LIHC, KICH, KIRC and KIRP. The HNSC box plot shows higher MIR589 RNA expression in tumor versus normal tissue (log2 FC = +1.204, t-test p < 0.001).
This table shows molecular features associated with MIR589 in patient tissues and cancer cell lines. In patient samples, MIR589 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
