MIR5680

Across TCGA patient cohorts, MIR5680 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,215 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR5680-associated GO terms across cancer lineages are Positive regulation of transcription elongation by RNA polymerase II, Nuclear-transcribed mRNA catabolic process, and Dendrite development. Each is linked with MIR5680 in more than 9 cancer types. Because this analysis shows association rather than direction, both MIR5680-to-partner and partner-to-MIR5680 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transcription elongation by RNA polymerase II grouped by MIR5680-low versus MIR5680-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR5680→partner) and Y-score (partner→MIR5680) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of transcription elongation by RNA polymerase II →	+0.101	+0.165	<.001	<.001	3	10
STAD	Nuclear-transcribed mRNA catabolic process →	+0.097	+0.120	<.001	.002	3	10
STAD	Dendrite development →	+0.047	+0.171	<.001	.001	3	9
BLCA	Facultative heterochromatin formation →	+0.048	+0.077	<.001	.001	3	9
STAD	Regulation of DNA recombination →	+0.068	+0.092	<.001	.002	2	10
STAD	Peptidyl-lysine modification →	+0.079	+0.178	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,215 associations by consensus.

Positive regulation of transcription elongation by RNA polymerase II by MIR5680 expression — STAD

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