MIR5591

Across TCGA patient cohorts, MIR5591 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,928 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR5591-associated GO terms across cancer lineages are Extrinsic apoptotic signaling pathway via death domain receptors, Microtubule polymerization, and Negative regulation of DNA metabolic process. Each is linked with MIR5591 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIR5591-to-partner and partner-to-MIR5591 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Extrinsic apoptotic signaling pathway via death domain receptors grouped by MIR5591-low versus MIR5591-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR5591→partner) and Y-score (partner→MIR5591) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Extrinsic apoptotic signaling pathway via death domain receptors →	+0.120	+0.256	<.001	<.001	3	5
STAD	Microtubule polymerization →	+0.123	+0.249	<.001	<.001	3	5
STAD	Negative regulation of DNA metabolic process →	+0.120	+0.225	<.001	<.001	3	5
STAD	Import into nucleus →	+0.132	+0.219	<.001	<.001	3	5
STAD	Establishment of RNA localization →	+0.150	+0.218	<.001	<.001	3	5
STAD	Regulation of cell division →	+0.107	+0.217	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,928 associations by consensus.

Extrinsic apoptotic signaling pathway via death domain receptors by MIR5591 expression — STAD

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