MIR5591

Across TCGA pan-cancer cohorts, MIR5591 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR5591’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MIR5591 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR5591 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

LIHC and LUAD are the cancer types where MIR5591 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR5591 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	II,III,IV	+0.263	.011	4	view →
LUAD	All	All	−0.088	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MIR5591–LIHC

Open the LIHC breakdown →