Across TCGA patient cohorts, MIR557 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR557-associated genes across cancer lineages are SLC16A12-AS1, MIR6882, and RNU6-445P. Each is linked with MIR557 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR557-to-partner and partner-to-MIR557 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR557→partner) and Y-score (partner→MIR557) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SLC16A12-AS1 →	+0.070	+6.469	<.001	.001	3	1
SKCM	MIR6882 →	+0.638	+5.680	<.001	.003	3	1
LUAD	RNU6-445P →	+0.497	+7.930	<.001	.008	3	1
SKCM	LGALS13 →	+0.067	+5.292	<.001	.006	3	1
SKCM	LINC02366 →	+0.072	+5.224	.003	.007	3	1
SKCM	MIR5190 →	+0.626	+5.159	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

MIR557 survival (RNA) · tumor vs normal (RNA) · all MIR557 data types