Q-omics provides the consensus-scored MIR550A3 profile across patient tissues and cancer cell-line models. MIR550A3 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, MIR550A3 is differentially expressed in 1, with the highest sampling consensus in KIRP. Additionally, MIR550A3 RNA expression shows 10,173 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight READ, KIRP, and GBM as cancer lineages where MIR550A3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR550A3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR550A3 survival associations across molecular data types. MIR550A3 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR550A3 RNA expression–survival associations across cancer types. High MIR550A3 expression shows unfavorable associations in READ, SKCM, COAD, PAAD and UVM, but favorable associations in LAML. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for MIR550A3 RNA expression.
This table summarizes MIR550A3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for MIR550A3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR550A3 shows higher tumor expression in KIRP. The KIRP box plot shows higher MIR550A3 RNA expression in tumor versus normal tissue (log2 FC = +0.485, t-test p = .030).
This table shows molecular features associated with MIR550A3 in patient tissues and cancer cell lines. In patient samples, MIR550A3 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
