MIR548Y

Across TCGA patient cohorts, MIR548Y RNA expression is significantly associated with the go_rna of many other GO terms, with 5,788 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR548Y-associated GO terms across cancer lineages are Telomere maintenance in response to DNA damage, DNA biosynthetic process, and Smoothened signaling pathway. Each is linked with MIR548Y in more than 9 cancer types. Because this analysis shows association rather than direction, both MIR548Y-to-partner and partner-to-MIR548Y results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance in response to DNA damage grouped by MIR548Y-low versus MIR548Y-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR548Y→partner) and Y-score (partner→MIR548Y) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance in response to DNA damage →	+0.084	+0.255	<.001	<.001	3	10
STAD	DNA biosynthetic process →	+0.104	+0.280	<.001	<.001	3	9
UCEC	Smoothened signaling pathway →	+0.086	+0.186	<.001	<.001	3	8
UCEC	Transport along microtubule →	+0.092	+0.091	<.001	<.001	3	8
UCEC	Protein-containing complex localization →	+0.097	+0.110	<.001	.001	3	8
STAD	Response to topologically incorrect protein →	+0.100	+0.237	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,788 associations by consensus.

Telomere maintenance in response to DNA damage by MIR548Y expression — STAD

Explore this box plot interactively →