MIR548Y

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR548Y RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR548Y data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MIR548Y RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR548Y expression acts as an unfavorable survival marker, although some lineages such as LIHC and SKCM show a favorable association.

LUAD, KICH, and KIRC are the cancer types where MIR548Y RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSTertileAll0.6380.818.00663view →
KICHOSTertileAll0.0820.877<.00151view →
KIRCDFSTertileIV0.0920.620.00236view →
THYMOSTertileII,III,IV0.5490.960.01118view →
KIRPDFSTertileAll0.6110.923.00618view →
UCECDFSTertileAll0.8140.898.03218view →
STADOSTertileII,III,IV0.5060.727.04212view →
LIHCDFSTertileIII,IV1.0000.148.02712view →
LGGOSTertileAll0.3160.530.0109view →
SKCMDFSTertileIII,IV0.6410.202.0443view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR548Y–LUAD (OS)

Kaplan–Meier survival curve for MIR548Y RNA-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration