MIR548V

Across TCGA pan-cancer cohorts, MIR548V RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR548V’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR548V RNA is repressed in tumor relative to normal tissue. In most cancer types MIR548V is over-expressed in tumor, although a few such as LUSC and KIRP show the opposite, repressed pattern.

LUSC, BRCA, and KICH are the cancer types where MIR548V tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR548V RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	−0.468	.004	3	view →
BRCA	All	IV	+0.755	<.001	2	view →
KICH	Female	All	+0.414	.037	2	view →
KIRP	All	All	−0.293	.008	2	view →
LUAD	Female	II,III,IV	−0.581	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MIR548V–LUSC

Open the LUSC breakdown →