MIR548S

Across TCGA patient cohorts, MIR548S RNA expression is significantly associated with the go_rna of many other GO terms, with 5,721 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR548S-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Glycerophospholipid metabolic process, and Peptidyl-lysine modification. Each is linked with MIR548S in more than 11 cancer types. Because this analysis shows association rather than direction, both MIR548S-to-partner and partner-to-MIR548S results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA metabolic process grouped by MIR548S-low versus MIR548S-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR548S→partner) and Y-score (partner→MIR548S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Negative regulation of mRNA metabolic process →	+0.039	+0.095	<.001	<.001	3	12
STAD	Glycerophospholipid metabolic process →	+0.030	+0.258	<.001	<.001	3	12
LUSC	Peptidyl-lysine modification →	+0.042	+0.089	<.001	.003	3	11
LUSC	Regulation of telomere maintenance via telomere lengthening →	+0.045	+0.112	<.001	<.001	3	11
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.042	+0.340	<.001	<.001	3	11
LUSC	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.048	+0.069	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,721 associations by consensus.

Negative regulation of mRNA metabolic process by MIR548S expression — LUSC

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