Across TCGA pan-cancer cohorts, MIR548E RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR548E’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MIR548E RNA is repressed in tumor relative to normal tissue. In most cancer types MIR548E is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

THCA, COAD, and KIRC are the cancer types where MIR548E tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR548E RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.223	<.001	5	view →
COAD	All	II,III,IV	−0.123	.024	2	view →
KIRC	All	All	+0.074	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MIR548E RNA expression & survival · all MIR548E data types