MIR548AN

Across TCGA pan-cancer cohorts, MIR548AN RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MIR548AN data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR548AN RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR548AN expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

UVM, DLBC, and HNSC are the cancer types where MIR548AN RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	III,IV	0.364	0.837	<.001	88	view →
DLBC	DFS	Tertile	All	0.453	1.000	<.001	88	view →
HNSC	OS	Tertile	III,IV	0.531	0.325	.004	76	view →
PAAD	OS	Tertile	All	0.499	0.236	<.001	67	view →
STAD	OS	Quartile	II,III,IV	0.818	0.457	.006	47	view →
BLCA	OS	Median	II,III,IV	0.759	0.655	.005	36	view →
UCEC	OS	Tertile	IV	0.066	0.755	<.001	36	view →
LUAD	DFS	Quartile	IV	0.484	0.936	.002	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
BRCA	DFS	Tertile	All	0.578	0.501	.020	24	view →
SKCM	OS	Tertile	II,III,IV	0.945	0.782	.002	24	view →
THYM	OS	Tertile	III,IV	0.212	1.000	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MIR548AN–UVM (DFS)

Open the UVM breakdown →