Q-omics provides the consensus-scored MIR548AN profile across patient tissues and cancer cell-line models. MIR548AN expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MIR548AN is differentially expressed in 10, with the highest sampling consensus in KIRC. Additionally, MIR548AN RNA expression shows 14,414 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UVM, and KIRC as cancer lineages where MIR548AN shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR548AN — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR548AN survival associations across molecular data types. MIR548AN RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR548AN RNA expression–survival associations across cancer types. High MIR548AN expression shows unfavorable associations in UVM, DLBC and UCS, but favorable associations in HNSC, PAAD and STAD. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for MIR548AN RNA expression.
This table summarizes MIR548AN tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR548AN. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR548AN shows lower tumor expression in LUAD, THCA and KICH and higher tumor expression in KIRC, HNSC and BLCA. The KIRC box plot shows higher MIR548AN RNA expression in tumor versus normal tissue (log2 FC = +0.899, t-test p < 0.001).
This table shows molecular features associated with MIR548AN in patient tissues and cancer cell lines. In patient samples, MIR548AN shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
