MIR548AC

Across TCGA patient cohorts, MIR548AC RNA expression is significantly associated with the go_rna of many other GO terms, with 6,443 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR548AC-associated GO terms across cancer lineages are Establishment of mitotic sister chromatid cohesion, Positive regulation of mRNA 3'-end processing, and Nucleotide-excision repair, DNA gap filling. Each is linked with MIR548AC in more than 15 cancer types. Because this analysis shows association rather than direction, both MIR548AC-to-partner and partner-to-MIR548AC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitotic sister chromatid cohesion grouped by MIR548AC-low versus MIR548AC-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR548AC→partner) and Y-score (partner→MIR548AC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Establishment of mitotic sister chromatid cohesion →	+0.087	+1.173	<.001	<.001	3	16
LAML	Positive regulation of mRNA 3'-end processing →	+0.083	+1.213	<.001	<.001	3	15
COAD	Nucleotide-excision repair, DNA gap filling →	+0.049	+0.134	<.001	.002	3	14
STAD	Sex-chromosome dosage compensation →	+0.045	+0.349	<.001	<.001	3	14
LAML	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.069	+1.000	<.001	.001	3	14
LAML	Positive regulation of mRNA processing →	+0.071	+1.128	<.001	.001	1	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,443 associations by consensus.

Establishment of mitotic sister chromatid cohesion by MIR548AC expression — LAML

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