MIR548AC

Across TCGA pan-cancer cohorts, MIR548AC RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MIR548AC’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR548AC RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR548AC is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LUSC, KIRC, and HNSC are the cancer types where MIR548AC tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR548AC RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.603	<.001	7	view →
KIRC	Male	All	−0.260	<.001	7	view →
HNSC	Male	All	+0.302	.011	4	view →
LIHC	All	All	+0.219	.003	3	view →
LUAD	Female	All	+0.340	.042	1	view →
KICH	All	II,III,IV	+0.189	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

MIR548AC–LUSC

Open the LUSC breakdown →