Across TCGA patient cohorts, MIR541 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR541-associated genes across cancer lineages are RN7SL591P, LINC02488, and MYCLP1. Each is linked with MIR541 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR541-to-partner and partner-to-MIR541 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR541→partner) and Y-score (partner→MIR541) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL591P →	+0.158	+5.097	.002	.008	3	1
SKCM	LINC02488 →	+0.382	+5.037	<.001	.009	3	1
SKCM	MYCLP1 →	+0.051	+4.979	.001	.009	3	1
SKCM	RBM22P3 →	+0.051	+7.219	.005	<.001	3	1
SKCM	LINC02558 →	+0.132	+5.224	<.001	.007	3	1
SKCM	LINC01392 →	+0.138	+5.224	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

MIR541 survival (RNA) · tumor vs normal (RNA) · all MIR541 data types