Across TCGA patient cohorts, MIR525 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR525-associated genes across cancer lineages are SEPTIN14P19, SGO1P2, and PSMB3P2. Each is linked with MIR525 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR525-to-partner and partner-to-MIR525 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR525→partner) and Y-score (partner→MIR525) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SEPTIN14P19 →	+0.026	+4.147	<.001	.008	3	1
SKCM	SGO1P2 →	+0.044	+4.784	<.001	<.001	3	1
SKCM	PSMB3P2 →	+0.127	+2.997	<.001	.009	3	1
SKCM	VDAC1P11 →	+0.107	+3.428	.002	.009	3	1
SKCM	PANCR →	+0.108	+3.678	<.001	.001	3	1
UCEC	OR1L4 →	+0.120	+4.661	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

MIR525 survival (RNA) · tumor vs normal (RNA) · all MIR525 data types