Across TCGA patient cohorts, MIR521-2 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR521-2-associated genes across cancer lineages are IGKV1OR-2, RN7SL627P, and MED13P1. Each is linked with MIR521-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR521-2-to-partner and partner-to-MIR521-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR521-2→partner) and Y-score (partner→MIR521-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV1OR-2 →	+0.520	+4.393	<.001	.002	3	1
UCEC	RN7SL627P →	+0.128	+4.442	<.001	.007	3	1
SKCM	MED13P1 →	+0.144	+7.816	<.001	.008	3	1
SKCM	RNU7-147P →	+0.347	+7.816	<.001	.008	3	1
UCEC	MIR4710 →	+1.625	+6.031	<.001	<.001	3	1
UCEC	RPL22P6 →	+0.134	+4.641	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

MIR521-2 survival (RNA) · tumor vs normal (RNA) · all MIR521-2 data types