MIR521-2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR521-2 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated MIR521-2 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher MIR521-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR521-2 expression acts as an unfavorable survival marker.

PAAD, UCEC, and STAD are the cancer types where MIR521-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PAADOSTertileAll0.1000.590<.00136view →
UCECOSTertileAll0.8550.929.01130view →
STADDFSTertileIII,IV0.2030.491.02518view →
SARCOSTertileAll0.1760.839.00118view →
LIHCDFSTertileAll0.2890.557.03318view →
TGCTDFSTertileAll0.6890.879.01312view →
THCADFSTertileIII,IV0.7000.926.0419view →
HNSCDFSTertileIII,IV0.1100.310.0446view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration