MIR497HG

Across TCGA pan-cancer cohorts, MIR497HG RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated MIR497HG data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR497HG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR497HG expression acts as an unfavorable survival marker, although some lineages such as UCEC and BRCA show a favorable association.

UVM, KICH, and UCEC are the cancer types where MIR497HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.368	0.809	<.001	152	view →
KICH	DFS	Quartile	II,III,IV	0.244	1.000	.002	64	view →
UCEC	DFS	Quartile	All	0.655	0.520	.011	36	view →
BRCA	OS	Tertile	III,IV	0.889	0.687	<.001	28	view →
LGG	DFS	Median	All	0.472	0.329	<.001	25	view →
SARC	OS	Quartile	All	0.913	0.750	.001	24	view →
LIHC	DFS	Median	All	0.600	0.484	.004	18	view →
ACC	OS	Tertile	All	0.310	0.909	.012	18	view →
PRAD	DFS	Median	All	0.693	0.876	.003	18	view →
LUAD	OS	Tertile	All	0.720	0.628	.015	17	view →
THCA	DFS	Quartile	IV	1.000	0.577	.009	16	view →
BLCA	DFS	Quartile	III,IV	0.157	0.454	.007	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

MIR497HG–UVM (DFS)

Open the UVM breakdown →