MIR497HG

Across TCGA pan-cancer cohorts, MIR497HG RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of MIR497HG’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MIR497HG RNA is repressed in tumor relative to normal tissue. In most cancer types MIR497HG is over-expressed in tumor, although a few such as BLCA and COAD show the opposite, repressed pattern.

BLCA, KIRC, and COAD are the cancer types where MIR497HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR497HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	IV	−2.117	<.001	11	view →
KIRC	Female	All	+0.957	<.001	11	view →
COAD	Male	II,III,IV	−0.844	<.001	11	view →
THCA	Male	III,IV	−0.552	<.001	11	view →
KICH	Female	All	−0.862	<.001	10	view →
KIRP	Male	All	−0.484	<.001	10	view →
LUAD	Female	III,IV	−0.910	<.001	9	view →
LUSC	Male	III,IV	−1.440	<.001	8	view →
UCEC	All	III,IV	−1.818	<.001	6	view →
BRCA	All	II,III,IV	−1.419	<.001	6	view →
READ	All	All	−1.076	.001	5	view →
HNSC	Male	All	−0.240	.005	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

MIR497HG–BLCA

Open the BLCA breakdown →