Across TCGA patient cohorts, MIR494 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MIR494-associated genes across cancer lineages are RNA5SP459, RNU6-365P, and IGLVI-42. Each is linked with MIR494 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR494-to-partner and partner-to-MIR494 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR494→partner) and Y-score (partner→MIR494) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP459 →	+0.276	+7.640	<.001	.009	3	2
BLCA	RNU6-365P →	+0.229	+7.640	<.001	.009	3	1
BLCA	IGLVI-42 →	+0.084	+7.640	<.001	.009	3	1
COAD	RNU6-1252P →	+0.526	+7.741	<.001	.009	3	1
COAD	MIR1263 →	+1.494	+7.741	<.001	.009	3	1
COAD	MIR1283-1 →	+0.726	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

MIR494 survival (RNA) · tumor vs normal (RNA) · all MIR494 data types