MIR4766

Across TCGA pan-cancer cohorts, MIR4766 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR4766’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MIR4766 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4766 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

HNSC, CHOL, and READ are the cancer types where MIR4766 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4766 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.131	.028	4	view →
CHOL	All	II,III,IV	+1.740	.011	2	view →
READ	All	III,IV	+0.890	<.001	2	view →
KIRC	All	All	+0.172	.018	2	view →
COAD	Male	IV	−0.506	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MIR4766–HNSC

Open the HNSC breakdown →