MIR4727

Across TCGA patient cohorts, MIR4727 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,239 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4727-associated GO terms across cancer lineages are Regulation of DNA recombination, Spindle assembly, and Mitochondrial gene expression. Each is linked with MIR4727 in more than 8 cancer types. Because this analysis shows association rather than direction, both MIR4727-to-partner and partner-to-MIR4727 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA recombination grouped by MIR4727-low versus MIR4727-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4727→partner) and Y-score (partner→MIR4727) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of DNA recombination →	+0.054	+0.571	<.001	.003	3	9
STAD	Spindle assembly →	+0.058	+0.282	<.001	<.001	3	8
STAD	Mitochondrial gene expression →	+0.059	+0.332	<.001	<.001	3	8
ESCA	mRNA 3'-end processing →	+0.060	+0.487	<.001	<.001	3	8
STAD	Positive regulation of mitotic cell cycle →	+0.053	+0.337	<.001	<.001	3	8
STAD	Mitochondrial transcription →	+0.051	+0.220	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,239 associations by consensus.

Regulation of DNA recombination by MIR4727 expression — ESCA

Explore this box plot interactively →