Across TCGA pan-cancer cohorts, MIR4692 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR4692’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR4692 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4692 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
BRCA, THCA, and LIHC are the cancer types where MIR4692 tumor–normal differential expression is most reproducible.