MIR4684

Across TCGA patient cohorts, MIR4684 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,997 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4684-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Receptor-mediated endocytosis, and Establishment or maintenance of cell polarity. Each is linked with MIR4684 in more than 11 cancer types. Because this analysis shows association rather than direction, both MIR4684-to-partner and partner-to-MIR4684 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by MIR4684-low versus MIR4684-high in BRCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4684→partner) and Y-score (partner→MIR4684) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	Negative regulation of gene expression, epigenetic →	+0.057	+0.104	<.001	<.001	3	11
HNSC	Receptor-mediated endocytosis →	+0.038	+0.052	<.001	.001	2	12
HNSC	Establishment or maintenance of cell polarity →	+0.048	+0.048	<.001	.001	3	11
HNSC	Canonical NF-kappaB signal transduction →	+0.051	+0.037	<.001	.004	3	11
KIRC	Positive regulation of cytoskeleton organization →	+0.049	+0.031	<.001	<.001	3	11
HNSC	Obsolete ncRNA transcription →	+0.057	+0.059	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,997 associations by consensus.

Negative regulation of gene expression, epigenetic by MIR4684 expression — BRCA

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