MIR4674

Across TCGA patient cohorts, MIR4674 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,625 significant associations in total. SARC shows the largest number of these associations.

The most reproducible MIR4674-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Telomere maintenance, and Regulation of protein folding. Each is linked with MIR4674 in more than 6 cancer types. Because this analysis shows association rather than direction, both MIR4674-to-partner and partner-to-MIR4674 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by MIR4674-low versus MIR4674-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4674→partner) and Y-score (partner→MIR4674) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Positive regulation of DNA metabolic process →	+0.043	+0.063	<.001	<.001	3	7
LUSC	Telomere maintenance →	+0.045	+0.060	<.001	.001	2	7
PAAD	Regulation of protein folding →	+0.040	+0.126	.001	<.001	3	6
LUSC	Thymus development →	+0.046	+0.068	<.001	<.001	3	6
LUSC	Obsolete regulation of histone methylation →	+0.074	+0.083	<.001	<.001	3	6
LUSC	Signal transduction in response to DNA damage →	+0.048	+0.063	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,625 associations by consensus.

Positive regulation of DNA metabolic process by MIR4674 expression — LUSC

Explore this box plot interactively →