MIR4674

Across TCGA pan-cancer cohorts, MIR4674 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR4674 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher MIR4674 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4674 expression acts as an unfavorable survival marker, although some lineages such as THYM and SARC show a favorable association.

DLBC, LIHC, and COAD are the cancer types where MIR4674 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	90	view →
LIHC	OS	Tertile	All	0.210	0.696	<.001	90	view →
COAD	OS	Tertile	III,IV	0.039	0.781	<.001	54	view →
LUAD	OS	Tertile	II,III,IV	0.153	0.750	<.001	36	view →
THYM	DFS	Tertile	II,III,IV	1.000	0.612	.024	18	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
SARC	OS	Tertile	All	1.000	0.478	.002	18	view →
UCEC	DFS	Tertile	All	1.000	0.632	.037	18	view →
UVM	OS	Tertile	All	0.302	0.710	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MIR4674–DLBC (OS)

Open the DLBC breakdown →