MIR4645

Across TCGA patient cohorts, MIR4645 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,107 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MIR4645-associated GO terms across cancer lineages are Regulation of establishment or maintenance of cell polarity, Positive regulation of GTPase activity, and Extrinsic apoptotic signaling pathway. Each is linked with MIR4645 in more than 27 cancer types. Because this analysis shows association rather than direction, both MIR4645-to-partner and partner-to-MIR4645 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of establishment or maintenance of cell polarity grouped by MIR4645-low versus MIR4645-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4645→partner) and Y-score (partner→MIR4645) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Regulation of establishment or maintenance of cell polarity →	+0.048	+1.137	<.001	<.001	3	28
THYM	Positive regulation of GTPase activity →	+0.030	+1.220	<.001	<.001	3	27
ESCA	Extrinsic apoptotic signaling pathway →	+0.041	+0.499	<.001	<.001	3	26
THYM	Negative regulation of peptidyl-tyrosine phosphorylation →	+0.049	+1.123	<.001	<.001	3	26
STAD	Regulation of B cell activation →	+0.053	+0.758	<.001	<.001	3	26
STAD	Myeloid cell development →	+0.044	+0.671	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,107 associations by consensus.

Regulation of establishment or maintenance of cell polarity by MIR4645 expression — THYM

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